Endocrine Abstracts

Recently a new procedure for measuring serum TSH receptor (TSHR) autoantibody (TRAb) was reported in which the autoantibodies inhibit binding of a human monoclonal thyroid stimulating antibody M22 (labeled with biotin) to TSHR-coated ELISA plate wells. This assay was termed 3rd generation TRAb assay. The aim of the present study was to clinically evaluate the TRAb 3rd generation assay in comparison with the 2nd generation TRAb assay (TRAb-2nd) based on the recombinant human TS...